The short answer is YES. While individual gallery policies vary, most will work with you to realize your dream. Below, Jamie Truppi of Bullseye shows some examples of the myriad possibilities for collaborations between client, artist, and gallery.
There are many artists, in all mediums, who will take commissions for fine art to fit the parameters of your home or business. Feeling inspired? Consult with your favorite PADA member gallery to see what you can make a reality.